Author: Admin

Wednesday, March 17, 2021

Yesterday, the state government of New South Wales (NSW), Australia announced “Bradfield” as the name for the planned third city in Greater Sydney.

Bradfield is located at west of City of Parramatta and Sydney, in vicinity of the then currently in construction Western Sydney International (Nancy-Bird Walton) Airport. The city is to be named in honour of John Bradfield, the engineer who designed the Sydney Harbour Bridge and Sydney rail line. The name came after a public consultation earlier last year.

In a press release on the New South Wales official website, Premier Gladys Berejiklian commented on the significance of the chosen name, “Bradfield was a renowned engineer who designed and oversaw the construction of both the Sydney Harbour Bridge and Sydney’s original railway network”. “The name Bradfield is synonymous with delivering game-changing infrastructure and it sets the right tone for the area we have referred to as the ‘Aerotropolis Core’ until now”, Berejiklian added.

According to the announcement, the planned city area is more than 1 km² (100 hectares) positioned to the north of the Bringelly suburb. In the official announcement, Premier Gladys Berejiklian wrote the city would be a “high-tech manufacturing and research hub” and it would create 200 thousand jobs. Premier Gladys Berejiklian clarified the scope of the planned city, saying “[t]his area will be transformed into a thriving city centre, home to advanced manufacturing, research, science and education and we want Bradfield to be as iconic as the existing major city centres of Sydney and Parramatta. […] What are paddocks now will be a thriving, bustling city centre offering the best job opportunities anywhere in Australia.”

Minister for Western Sydney Stuart Ayres commented on the prior public consultation and the large community involvement, saying “The number of suggestions the community put forward to ‘Name the Place’ was overwhelming and we are thrilled with the level of participation and interest this project attracted. […] We thank everyone for having their say and want to assure the community the remaining suggestions will be considered as names for streets, parks and other landmarks in the new city centre. […] I look forward to Bradfield being the first name that people think of when starting a new job, creating a new business, learning a new skill and investing in NSW.”

Per a report from Sydney Metro published in June 2020, the Western Sydney International project of the airport and the metro is planned to be inaugurated in 2026.

With some comments on social media having indicated concerns over the hotter climate in the area, Wikinews has retrieved the mean maximum temperatures for the three areas — Sydney, Parramatta, and Badgerys Creek location — and has found arithmetic mean of annual of monthly mean maximum temperatures for these locations to be 23.13, 23.8 and 24.04° Celsius, according to the data from 1996 to 2020 from the Bureau of Meteorology.

According to official data from local authorities, City of Sydney was founded in 1842 and has an area of 26.15 km²; while Sydney was converted from a penal colony in the year of 1788. Parramatta was also founded in 1788, and has an area of 84 km².

Saturday, October 1, 2011

Last week, Nature Genetics carried twin studies into the genetics of bipolar disorder and schizophrenia. This special report examines the month’s research into the illnesses in detail, with Wikinews obtaining comment from experts based in Australia, the United States, and the United Kingdom ahead of the U.S. Mental Illness Awareness Week, which starts tomorrow.

Eleven genetic regions were identified; seven of these were for schizophrenia and five of those were hitherto undiscovered. The parallel studies, conducted separately, examined more than 50,000 people worldwide and identified two genetic loci associated with both diseases.

Little is known about the two illnesses, each of which affects around 1% of people and is treated with strong medication. Bipolar sufferers experience extremes of mood – depression and mania, hence the previous name “manic depression” for the illness. Schizophrenia is associated with hearing voices, chaotic thoughts, and paranoia. There is no known cure.

The latest research examined both the healthy and the afflicted, using computers to scan genomes. Inheritance was thought to be a factor from prior knowledge of the diseases as a familial trait, but the original desire had been to isolate a single faulty gene. Instead it has become apparent that the genetic factors are many; in the case of schizophrenia, at most around 30% of the genetic components are thought to have been identified.

The University of Chicago’s Pablo Gejman, a lead researcher on the schizophrenia study, explained to Wikinews in a telephone interview from Buenos Aires, Argentina that “One of the goals of genetic research is to find druggable targets” – to “find treatments at the root of the problem”.

Whilst noting that there is no guarantee the genetic code identified is druggable, Gejman named calcium-activated neurochemical channels in the brain as candidates for new drugs. The channels were linked to schizophrenia in the study.

Gejman explained that a genetic locus called mir137 “suggests an abnormality of gene regulation.” The diseases are so poorly understood that it is uncertain if they are in fact two components of a single spectrum, or even each comprised of multiple illnesses.

The new and “provocative data” gathered showed the significant loci identified were “not part of the pre-existent hypothesis.” Calling this “interesting”, Gejman added that the team found no evidence that dopamine receptors are involved; current drug treatments target dopamine receptors. The findings are “not related to anything we thought we knew [about schizophrenia],” he told our correspondent.

Quizzed about the possibility variations in the genetic factors involved in expressing the diseases explained the variation seen in symptoms, Gejman was uncertain. “We will have the answer, probably, only when we sequence the whole [human] genome.” He notes that the relationship between genotype and phenotype is unclear, and that “We know very little of the genetic architecture of schizophrenia and” other disorders.At the time the results were published, participating scientist Professor Rodney Scott from the University of Newcastle in Australia said “The strength of this research is in the numbers. The findings are robust and give us a lot of statistical power to identify the genetic determinants of schizophrenia.” Scott told Wikinews that “If any single centre tried to undertake such a study, it would require millions of pounds. Since it was a collection of data from across the world the costs were spread. In this era of financial difficulty it will become increasingly difficult to secure funding for this type of project even though the pay-offs will be significant.”

Gejman expressed similar sentiment. “The research budget is not growing, which makes [funding] difficult,” he said, though he felt the cost “is not prohibitive because of the benefits.” “I think that it was money well invested” and “very well spent for the future,” he said, adding that organisations in Europe and the US were aware of the importance of such research.

Gejman also agreed on reliability – the study is “Very reliable because of the sample size; that should provide robust results… [we] have worked with a much larger sample than before.” Scott told us it was “a highly reliable study” that has the potential to lead to new treatments “in the long run”.

Another point was the two genetic loci identified as common to both – how much support do they lend to the notion the diseases are linked? “Until more information is available it is really only suggestive,” says Scott. “Strong enough to say there may be potentially a common pathway that bifurcates to give rise to two diseases.”

“It is an excellent demonstration,” said Gejman “because you have the same chains that are common to both disorders, in fact not just the same chains but also the same alleles.” He stressed uncertainty in how strong the relationship was, however.

Scott said examining how the variation of genetic factors may translate into varied symptoms being expressed “certainly is a good target for future research”; “It is not known how many genetic factors contribute to either of these diseases but it is likely that not all are necessary to trigger disease.” “New questions will always arise from any major study,” he told our reporter. “Certainly, new questions about bipolar and schizophrenia are now able to be formulated on the basis of the results presented in the two reports.”

These weren’t the only studies to look at the two diseases together in September. The British Medical Journal carried research by a team from the University of Oxford and King’s College London that examined mortality rates in England for schizophrenia and bipolar sufferers. They found both groups continued to suffer higher mortality rates than the general population – whilst these included suicides, three quarters of deaths were down to ailments such a s heart conditions. General death rates dropped from 1999 to 2006, but sufferers below 65 saw their death rate remain stable – and the over-65 saw theirs increase.

“By 2006, the excess risk in these groups had risk to twice the rate of the general population, whereas prior to that it had only been 1.6 times the risk, so it increased by almost 40%,” said Dr Uy Hoang of Oxford. The study looked at every discharged inpatient with a diagnosis of either condition in England in the relevant time.

Hoang said at the time of the research’s release that doctors should devote attention to predicting and preventing physical illness associated with mental disorders. His study comes at a time when the UK has launched a “no health without mental health” strategy which does attempt to screen for physical illnesses coinciding with mental illnesses. The government aims to reduce the death rate of those with mental disorders.

Rodney Scott described this research result to Wikinews as “Possibly” connected to genetic association with other hereditary ailments, such as cardiovascular disease; he told us another possibility is that “The continued raised mortality rates may be associated with the diseases themselves.”

“We believe the NHS [National Health Service] and Department of Health need to do more to support research and service development for people with bipolar disorder,” Wikinews was told by Suzanne Hudson, Chief Executive of London-based British charity MDF The Bipolar Organisation. “The provision of specialist services for bipolar is very limited in the UK and the demand for our services is unprecedented.”

“A genetic test for bipolar would be a useful tool but the science and ethics are very complex,” Hudson told us, referring to the Nature Genetics genetic study. “Just because someone has ‘bipolar genes’ does not mean they might go on to develop it. Family studies of bipolar show that this is a likely outcome of genetics research in this area. Even if it were possible to accurately predict bipolar in this way, questions about how you treat that person are difficult. For example do you start medication that is not necessary at that point in time?”

“Current treatment is not satisfactory” because it does not always work and has “side effects,” Gejman told us. Robert Whitaker, a US medical journalist and book author, told an audience in New Zealand at the end of August that evidence suggests antidepressant drugs may make children and teenagers worse – “You see many become worse and end up with a more severe diagnosis, like bipolar illness,” and the suicide risk may increase.

Whitaker blames commercial interests. “The adult market appeared saturated, and so they began eying children and teenagers. Prior to this, few children and youth were seen as suffering from major depression, and so few were prescribed anti-depressants.”

One possible alternative, raised by a connection between depressive illness and inflammation, is aspirin and similar compounds. “The link between inflammation and mood disorders has been known for sometime and the use of aspirin and other drugs in depression is now becoming more common in the literature,” Hudson says. “Any new treatments for bipolar, which is a very complex and co-morbid illness, has to be a good thing.”

Professor Dr. Michael Berk, chairman of psychiatry at Australia’s Deakin University, recently gave a talk to just this effect. Speaking at this year’s Congress of the European College of Neuropsychopharmacology, held this past month, he also highlighted statins as a treatment. Recognising the link to physical ailments, he told an interviewer “The brain does not exist in isolation, and we need to understand that pathways similar to those that underpin risks for cardiovascular disorders, stroke, and osteoporosis might also underpin the risk for psychiatric disorders, and that other treatments might be helpful.”

Berk also touched upon speed of diagnosis and treatment; “Early interventions can potentially improve the outcome” of bipolar sufferers, he told his audience. MDF The Bipolar Organisation claim an average of ten years is possible before a person is diagnosed. “This clearly is an issue, if we believe that earlier diagnosis and treatment facilitate better outcomes,” Berk told Wikinews. Though he questions the effectiveness of currently-used drugs on advanced bipolar cases, he does not go so far as to say drugs are actively harmful. He told us “it appears that our best treatments work best earlier in the illness course; and that seems to apply to psychotherapy and pharmacotherapy.”

Berk has already performed research using statins which suggests they can form a treatment. He now seeks funding for research involving aspirin. On funding, he tells Wikinews “psychiatric disorders comprise between 16% and 22% of the burden of disability (depending on who measures it), attracts^[sic] just over 6% of the clinical budget at least in Australia and 3% of the research budget. Research as a discretionary spending item is at great risk.”

Berk’s research, in the past, has been funded by companies including GlaxoSmithKline. Hudson told Wikinews this did not concern her charity; in fact, they welcomed it. “We believe it is important pharmaceutical companies continue to invest in the development of new medications for bipolar. This is how it works in all other health specialities and mental health should be no different.”

“There is a need for greater education for mental health professionals and GPs [general practitioners] about bipolar [in the UK],” she told us. “As the national bipolar charity we receive many, many calls and requests from GPs and other health professionals for our leaflets and information sheets which is fantastic. We very much welcome opportunities to work together for the benefit of individuals affected by bipolar.”

Wikinews contacted the UK’s National Institute for Clinical Excellence (NICE) to discuss issues raised in this article, including future treatments, genetic screening, and mortality rates. NICE did not respond.

Might statins and/or aspirin improve treatment – might they be cheaper, perhaps, or safer? “This is an area of research promise,” says Berk, “however it is too early to make any clinical treatment claims; [all] we can say is that this needs to be studied in properly designed trials capable of giving a more definitive answer.” And what of possible explanations for the increased mortality rate observed in England? Should researchers look at whether bipolar influences more than just the brain, or if it is linked to other genetic conditions?

“For sure,” he told us. “There is new evidence that similar pathways contribute to the risk for both medical and psychiatric illness, both in terms of lifestyle factors, and biomarkers of risk.”

Friday, May 4, 2007

The Northern Ireland loyalist paramilitary group, the Ulster Volunteer Force (UVF) intends to end its decade-long campaign of violence and terror and will disarm, making it the first loyalist paramilitary to do so.

However, unlike the Provisional Irish Republican Army, the UVF will not fully decommission weapons. Instead the illegal organization will put weapons “beyond reach” of ordinary members in secure caches only known to UVF leadership.

The group, considered a terrorist group in both the United States and United Kingdom issued a statement, read by Gusty Spence, a founding member of the UVF, which stated that “as of 12 midnight, Thursday 3 May 2007, the Ulster Volunteer Force and Red Hand Commando will assume a non-military, civilianised, role.”

It also added, “All recruitment has ceased; military training has ceased; targeting has ceased and all intelligence rendered obsolete; all active service units have been deactivated; all ordinance has been put beyond reach and the IICD instructed accordingly.”

However, according to the Independent International Commission on Decommissioning (IICD), this does not meet the requirements set out in government legislature. Although it welcomed the news of disarmament, the Commission said it was “concerned by [the UVF’s] intention to deal with their arms without the involvement of the IICD”.

Irish Prime Minister Bertie Ahern suggested the UVF work with the Commission “with a view to full decommissioning”. Sinn Fein welcomed the news of UVF’s disarmament. “This is a welcome statement if it signals a recognition of the new political reality where there is no room for armed or violent actions,” said John O’Dowd of Sinn Fein.

The British Prime Minister’s office expressed cautious optimism over the UVF announcement. “We need to see how today’s announcement is translated into action,” said a spokesman for Prime Minister Tony Blair.

The group has been on a cease-fire since 1994 in response to the IRA ceasefire. The group was responsible for 427 deaths during the violent period in Northern Ireland known as the “the Troubles” some of which was notoriously violent, which included a group of members known as the “Shankill Butchers” who committed a series of grisly murders of Catholics in Belfast and the Dublin and Monaghan bombings, which claimed the life of 33 victims and was the deadliest terrorist incident during the Troubles to happen in the Republic of Ireland.

Monday, September 2, 2013

Nelson Mandela has left hospital to return to his home in Johannesburg, in a critical condition, South African officials said on Sunday.

The 95-year-old anti-apartheid leader and former South African president has spent nearly three months in hospital for treatment of a recurring lung infection and has returned to his residence in Johannesburg where he will continue to recover.

A statement from the office of current South African president Jacob Zuma confirmed Mandela homecoming:

“His teams of doctors are convinced that he will receive the same level of intensive care at his Houghton home that he received in Pretoria.”

“His home has been reconfigured to allow him to receive intensive care there. The health care personal providing care at his home are the very same who provided care to him in hospital.”

Several ambulances and TV crews gathered outside Mandela’s home in the Houghton suburb of Johannesburg on Sunday, where well-wishers gathered to pray for his recovery.

Mandela’s last public appearance was at the 2010 football World Cup, held in South Africa.

Wednesday, February 22, 2006

Almost 600 desperate family members and others remained camped outside the Pasta de Conchos coal mine near San Juan de Sabinas, in the northern Mexico state of Coahuila where 65 Mexican miners were trapped by a gas explosion around 2:30 a.m. (0830 GMT) Sunday. Some are threatening to storm the mine while soldiers are trying to keep them calm and rescuers continue to pick through the rock and debris with hand tools, fearing that any power equipment might set off another explosion.

The local newspaper’s headline caused panic by quoting one of over a dozen surviving miners who were close enough to the exits to escape: “They are surely dead,” (La Prensa de Monclova). However, Arturo Vilchis, Civil Protection Director, refused to speculate on the condition of the miners, while Javier de la Fuente, an engineering contractor with mine owner Grupo México S.A. de C.V. also tried to hold out some hope.

The men were each supposed to be carrying oxygen tanks, each with a six hour supply, and there’s some hope that they could reach other oxygen supply tanks, or that some air might be reaching them through the ventilation shafts into which rescuers have been pumping more oxygen since shortly after the explosion.

Juan Rebolledo, vice president of international affairs for Grupo México, assured onlookers that U.S. mining experts were on the way, and officials at the U.S. Mine Safety and Health Administration have confirmed that they’ve sent a specialized equipment truck and several mining experts which should arrive at the mine site on Wednesday afternoon.

Meanwhile Consuelo Aguilar, a spokeswoman for the National Miners’ Union, called for an investigation into Grupo México’s responsibility for the disaster. Pedro Camarillo, a federal labor official, said nothing unusual was found during a routine evaluation in early February.

Wednesday, April 25, 2007

The Iranian police forces have faced criticism from Ayatollah Hashemi Shahrudi, the head of the judiciary who was appointed by Grand Ayatollah Ali Khamenei, for their re-invigorated campaign to do away with un-Islamic dress.

Ayatollah Shahroudi proclaimed, “Tough measures on social problems will backfire and have counter-productive effects.” Others have, of course, made it clear that un-Islamic dress can lead to moral corruption, engender innumerable vices, and hurt the Islamic character of the nation.

Some believe that no one had any issue with the creation of an Islamic atmosphere. The core of the matter revolves around the implementation of the Islamic dress code; additionally, heavy-handed measures should be shunned. For instance, Mehdi Ahmadi, information head of Tehran’s police, told Al Jazeera: “Some citizens may complain about the way the law is being enforced but they all agree with the plan itself.”

According to one student, “You simply can’t tell people what to wear. They don’t understand that use of force only brings hatred towards them, not love.” Nevertheless, Hojatoll-Islam Mostafa Pour-Mohammadi, Iran’s interior minister who is in charge of policing, prognosticated positive feedback from the populace when he said, “People are unhappy with the social and moral status of the society. They expect that the fight against social insecurity be properly implemented.” Thus, Hujjat al-Islam Pour-Mohammadi re-iterated the necessity of proper implementation and methodology towards the restoration of morality in the Islamic Republic. Islamic officials and religious people affirm that this is indispensable to promote righteousness, curb sin, and bring open sinners to justice.

Following the Islamic Revolution in 1979, hijab became mandatory in Iran for every woman including foreigners after over 98% of citizens voted for an Islamic government. Women may face caning up to 74 strokes for failing to observe hijab. In this recent crackdown, the authorities have arrested many citizens throughout the country. Not only have women been taken into custody for their hair being uncovered on their foreheads and tight clothes that show body shapes, For men they need to cover from knee to their waist as according to Sharia. Even a foreign journalist was detained because the photograph on her press card was indecent.

It has not been clear whence the directive for the re-newed clampdown emanated. Some have blamed Mahmoud Ahmadinejad while Gholam Hossein Elham, the government spokesman, stated to reporters, “The police work as agents of the judiciary to confront crimes. The government as an executive body does not interfere in the affairs of the judiciary.” The following pre-election speech seems to corroborate this latter statement: